𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Application of LC-SIM-MS in drug assay development

✍ Scribed by P. Heizmann; R. Gössl; R. Herissé

Publisher
Springer
Year
2000
Tongue
English
Weight
265 KB
Volume
52
Category
Article
ISSN
0009-5893

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Determination of lipoic acid in rat plas
Determination of lipoic acid in rat plasma by LC-MS/MS with electrospray ionization: Assay development, validation and application to a pharamcokinetic study
✍ Ravi Kumar Trivedi; Raja Reddy Kallem; Rao N. V. S. Mamidi; Ramesh Mullangi; Nug 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 149 KB 👁 2 views

## Abstract A simple, sensitive and specific LC‐MS/MS method for the determination of lipoic acid was developed and validated over the linearity range 5–1000 ng/mL (__r__^2^ > 0.99) with 200 µL rat plasma using rosigliatzone as an internal standard (IS). The assay procedure involved a simple one‐st