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Application of family-based tests of association for rare variants to pathways

✍ Scribed by Brian Greco,Alexander Luedtke,Allison Hainline,Carolina Alvarez…

Book ID
126380012
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
166 KB
Volume
8
Category
Article
ISSN
1753-6561

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In anticipation of the availability of next-generation sequencing data, there has been increasing interest in association analysis of rare variants (RVs). Owing to the extremely low frequency of a RV, single variant-based analysis and many existing tests developed for common variants may not be suit