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Application of amplified RNA and evaluation of cRNA targets for spotted-oligonucleotide microarray

✍ Scribed by Jik Young Park; Su Young Kim; Jong Heun Lee; Jaehwi Song; Ji Heon Noh; Sug Hyung Lee; Won Sang Park; Nam Jin Yoo; Jung Young Lee; Suk Woo Nam


Book ID
116289493
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
947 KB
Volume
325
Category
Article
ISSN
0006-291X

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## Abstract Two complementary oligonucleotides were conjugated with terpyridine ligands at their nearby 5′‐ and 3′‐ends. Addition of a stoichiometric amount of a transition metal (Zn^2+^, Fe^2+^) resulted in a large increase in the melting temperature of the duplex. The conjugation of TPY to stem‐l