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Application of 15N Nuclear Magnetic Resonance Spectroscopy to the Determination of the Stability of Aryl Nitrogen Mustards

✍ Scribed by Wilman, Derry E. V.; Palmer, Brian D.; Denny, William A.

Book ID: 127159307
Publisher: American Chemical Society
Year: 1995
Tongue: English
Weight: 299 KB
Volume: 38
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00012a027

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## Abstract By comparison of p__K__^a^ values derived from ^15^N and ^13^C nuclear magnetic resonance (NMR) spectroscopies, the assignment of the ^15^N resonances of apramycin is completed. ^13^C NMR spectra appear to provide accurate p__K__~a~ determinations with this aminoglycoside. Hydroxylation