## Abstract To determine whether the use of ethyl alcohol (ethanol, C~2~H~5~ OH) may increase the liver damage caused by hepatitis B virus infection, ethanol was infused into four chimpanzees on one or two occasions during the course of natural or experimentally induced hepatitis B virus infections
Appearance of immune complexes during experimental hepatitis A infection in chimpanzees
โ Scribed by Harold S. Margolis; Omana V. Nainan; Krzysztof Krawczynski; Daniel W. Bradley; James W. Ebert; John Spelbring; Howard A. Fields; James E. Maynard
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 847 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0146-6615
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Circulating immune complexes were isolated by conglutinin affinity chromatography during the course of hepatitis A virus infection in a chimpanzee. Characterization of circulating immune complexes showed that most of the hepatitis A virus-specific antibody was IgM, that IgG was present and that C3d
## Abstract Experimental infection of two chimpanzees with the Phoenix Antigen strain of HAV resulted in the cyclic excretion of virus particles on days 9โ11, 14โ15, and 20โ21 postinoculation. Isopycnic banding in CsCl of stool suspensions prepared from 9โ11; 14โ15;and 17, 19, 21 dav stool pools re
## Abstract Two study chimpanzees were inoculated intravenously with approximately 1,000 chimpanzee infectious doses of hepatitis B virus (HBV), one with subtype adr and one with subtype ayw, each previously incubated with 0.1 ml of a murine monoclonal antibody (IgG ~1(K)~ class) directed against a
## Abstract Passive transfer of antibodies to hepatitis A virus (HAV) in immune globulin (IG) effectively prevents hepatitis A when given after exposure, but does not provide lasting protection from infection. Hepatitis A vaccines have been shown to generate quickly levels of antibody equivalent to