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Appearance and disappearance of Syk family protein-tyrosine kinase genes during metazoan evolution

✍ Scribed by Robert E. Steele; Nicholas A. Stover; Masahiko Sakaguchi


Book ID
117523825
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
732 KB
Volume
239
Category
Article
ISSN
0378-1119

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Genes encoding two members of the JAK family of protein tyrosine kinases, Jak-1 and Jak-2, have been mapped to mouse Chromosomes (Chrs) 4 and 19 respectively. These placements are consistent with the previously described location of human JAK1 and JAK2, which lie in regions of synteny on human Chrs