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APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis

✍ Scribed by Leslie Crews; Edward Rockenstein; Eliezer Masliah

Publisher
Springer
Year
2009
Tongue
English
Weight
601 KB
Volume
214
Category
Article
ISSN
0340-2061

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## Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with senile β‐amyloid (Aβ) plaques and cognitive decline. Neurogenesis in the adult hippocampus is implicated in regulating learning and memory, and is increased in human postmortem brain of AD patients. Howe