A method was devised for preparing (S)-(+)-apomorphine from (R)-(-)-apomorphine. Dehydrogenation of the dimethyl ether of (R)-(-)-apomorphine with 10% palladium-on-carbon followed by reduction with sodium cyanoborohydride under acidic conditions resulted in quantitative racemization to give (R,S)-ap
Aporphines V: Total synthesis of (±)-apomorphine
✍ Scribed by John L. Neumeyer; Bernard R. Neustadt; Klaus K. Weinhardt
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 317 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0022-3549
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## Abstract Analogues of apomorphine **(1)** having the catechol moiety replaced by pyrrole (→**10**, **18**), pyrazole (→**12**), isoxazole (→**13**, **14**), thiazole (→**16**) and thiadiazole (→**20**) ring systems have been synthesized from the key intermediate ketone **6**.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v