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Structural Analogues Of Aporphines Part 1: Synthesis of Apomorphines with the Catechol Moiety Replaced by 5-membered Heterocycles

✍ Scribed by Daniel Berney; Karlheinz Schuh

Publisher: John Wiley and Sons
Year: 1982
Tongue: German
Weight: 325 KB
Volume: 65
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.19820650421

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✦ Synopsis

Abstract

Analogues of apomorphine (1) having the catechol moiety replaced by pyrrole (→10, 18), pyrazole (→12), isoxazole (→13, 14), thiazole (→16) and thiadiazole (→20) ring systems have been synthesized from the key intermediate ketone 6.

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