𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Apoptotic cell death in vulnerable subpopulation of cerebellar granule cells

✍ Scribed by A. Hara; Masayuki Niwa; Naoki Yoshimi; Hideki Mori

Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
14 KB
Volume
94
Category
Article
ISSN
0001-6322

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Lysophosphatidylcholine protects cerebel
Lysophosphatidylcholine protects cerebellar granule neurons from apoptotic cell death
✍ Yutaka Ikeno; So-hyun Cheon; Naoko Konno; Ayako Nakamura; Katsuhiko Kitamoto; Ma πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 254 KB

## Abstract Cultured cerebellar granule neurons (CGNs) undergo apoptosis when deprived of depolarizing stimulation and provide an in vitro model system with which to study the effects of neurotrophic substances. Our previous results showed that secretory phospholipases A~2~ (sPLA~2~s) protect CGNs

Role of oxidative stress in the apoptoti
Role of oxidative stress in the apoptotic cell death of cultured cerebellar granule neurons
✍ Antonio Valencia; Julio MorΓ‘n πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 411 KB πŸ‘ 2 views

When cultured cerebellar granule neurons (CGN) are transferred from 25 mM KCl (K25) to 5 mM KCl (K5) caspase-3 and caspase-8, but not caspase-1 or caspase-9,activities are induced and cells die apoptotically. CGN death was triggered by a [Ca(2+)](i) modification when [Ca(2+)](i) was reduced from 300

Antioxidants J811 and 17Ξ²-estradiol prot
Antioxidants J811 and 17Ξ²-estradiol protect cerebellar granule cells from methylmercury-induced apoptotic cell death
✍ E. DarΓ©; M.E. GΓΆtz; B. Zhivotovsky; L. Manzo; S. Ceccatelli πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 397 KB

Cerebellar granule cells (CGC) have provided a reliable model for studying the toxicity of methylmercury (MeHg), a well-known neurotoxicant contaminating the environment. In the present study we report that doses of MeHg ranging from 0.1 microM to 1.5 microM activated apoptosis, as shown by cell shr

Pigment epithelium-derived factor (PEDF)
Pigment epithelium-derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apoptotic cell death
✍ Takehisa Araki; Takayuki Taniwaki; S. Patricia Becerra; Gerald J. Chader; Joan P πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 189 KB

We have shown previously that pigment epitheliumderived factor (PEDF) acts as a survival factor for cerebellar granule cell neurons in culture, as well as protecting them against glutamate toxicity. In this study we have examined effects of PEDF on apoptotic cell death. We find that the granule cell