## Abstract ## BACKGROUND. XIAPโassociated factor 1 (XAF1) negatively regulates the function of the Xโlinked inhibitor of apoptosis protein (XIAP), a member of the IAP family that exerts antiapoptotic effects. The extracellular signalโregulated kinase (ERK) pathway is thought to increase cell prol
Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates lipopolysaccharide-induced tissue factor expression in pulmonary microvasculature
โ Scribed by Kenji Mizumura; Yasuhiro Gon; Fumio Kumasawa; Akira Onose; Shuichiro Maruoka; Ken Matsumoto; Shinichi Hayashi; Tomoko Kobayashi; Shu Hashimoto
- Book ID
- 116576731
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 533 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1567-5769
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Transforming growth factor (TGFโฮฒ1) is a potent inducer of chondrogenesis and stimulant of cartilage extracellular matrix (ECM) synthesis. Tissue inhibitor of metalloproteinasesโ3 (TIMPโ3) is located in ECM and is the major inhibitor of matrix metalloproteinases (MMPs) and aggrecanase,
## ABSTRACT Cigarette smoking is strongly implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mucus hypersecretion is the key manifestation in patients with COPD and mucin 5AC (MUC5AC) is a major component of airway mucus. Hypoxia inducible factorโ1 (HIFโ1) is a transcri