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A novel function of peroxiredoxin 1 (Prx-1) in apoptosis signal-regulating kinase 1 (ASK1)-mediated signaling pathway

✍ Scribed by So Yong Kim; Tae Jin Kim; Ki-Young Lee


Book ID
113620812
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
311 KB
Volume
582
Category
Article
ISSN
0014-5793

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## Abstract ## BACKGROUND. XIAP‐associated factor 1 (XAF1) negatively regulates the function of the X‐linked inhibitor of apoptosis protein (XIAP), a member of the IAP family that exerts antiapoptotic effects. The extracellular signal‐regulated kinase (ERK) pathway is thought to increase cell prol