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Apoptosis resistance and immune escape mechanisms of bladder cancer cells

✍ Scribed by Patricia L. Willert; Frank G.E. Perabo; Stefan Kamp; Doris H. Schmidt; Andreas Wirger; Peter Albers; Stefan C. Müller

Book ID: 117657720
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 106 KB
Volume: 37
Category: Article
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(01)80349-x

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## Abstract Discovery of the B cell lymphoma gene 2 (__Bcl‐2__ gene) led to the concept that development of cancers required the simultaneous acquisition, not only of deregulated cell division, but also of resistance to programmed cell death or apoptosis. Apoptosis is arguably the common pathway to