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Apoptosis-Linked Gene 2 Binds to the Death Domain of Fas and Dissociates from Fas during Fas-Mediated Apoptosis in Jurkat Cells

✍ Scribed by Yong-Sam Jung; Keun-Soo Kim; Kwang Dong Kim; Jong-Seok Lim; Jung-Woo Kim; Eunhee Kim


Book ID
115588821
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
224 KB
Volume
288
Category
Article
ISSN
0006-291X

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## Abstract It is widely known that death receptor Fas‐dependent apoptotic signals are associated with development of prostate cancer, but the key pathways involved in sensitivity to the apoptosis remain unclear. Here we investigated the molecular mechanism by which 2‐methoxyestradiol (2‐ME) effect