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Apoptosis-inducing effect of Jinke on Molt-4 cells and its mechanism

✍ Scribed by Zhenchuang Zhu; Yixin Tong; Yangping Yue; Yu Deng; Dongdong Yu; Wei Xiao; Xiaolan Li; Deding Tao; Junbo Hu; Jianping Gong

Publisher: Springer
Year: 2008
Tongue: English
Weight: 770 KB
Volume: 7
Category: Article
ISSN: 1610-1979
DOI: 10.1007/s10330-008-0067-2

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## Abstract We examined the ability of the synthetic selenium compound, 2‐(4‐methylphenyl)‐1,3‐selenazol‐4‐one (hereafter designated **3a**), to induce apoptosis in a human ovarian cancer cell line (SKOV3) and a human leukemia cell line (HL‐60). Flow cytometry showed that **3a** treatment induced a