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Apoptosis in Rat Cardiac Myocytes Induced by Fas Ligand: Priming for Fas-mediated Apoptosis with Doxorubicin

✍ Scribed by Minako Yamaoka; Seiji Yamaguchi; Takahiko Suzuki; Masaki Okuyama; Joji Nitobe; Norio Nakamura; Youji Mitsui; Hitonobu Tomoike


Book ID
115633010
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
727 KB
Volume
32
Category
Article
ISSN
0022-2828

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Background and Objectives: Fas (APO-1) induces apoptosis after binding Fas ligand (FasL). Evidence suggests that tumors may use this interaction to evade the host immune response. Fas/FasL expression has not been reported in esophageal cancer. We hypothesized that Fas expression would render esophag