## AMAs are detectable by indirect immunofluorescence (IF) We examined the clinical usefulness of measurements on tissue substrates in 93% to 99% of patients with PBC, but of antimitochondrial autoantibodies (AMA) in prethis method also detects AMAs of differing specificities in dicting disease pr
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Apoptosis-associated antigens recognized by autoantibodies in patients with the autoimmune liver disease primary biliary cirrhosis
โ Scribed by Christoph Peter Berg; Gerburg Maria Stein; Hildegard Keppeler; Michael Gregor; Sebastian Wesselborg; Kirsten Lauber
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 563 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1360-8185
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Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, non