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Apoptosis as a Measure of Chemosensitivity to Cisplatin and Taxol Therapy in Ovarian Cancer Cell Lines

✍ Scribed by Randall K. Gibb; Douglas D. Taylor; Tina Wan; Dennis M. O'Connor; David L. Doering; Çiçek Gerçel-Taylor

Book ID
115617147
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
306 KB
Volume
65
Category
Article
ISSN
0090-8258

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The ability of lonidamine (LND), an energolytic derivative of indazole-carboxylic acid, to modulate the cytotoxicity of Taxol (TX) was investigated in the A2780 human ovarian cancer cell line. Different cytotoxicity results were obtained as a function of treatment schedule. Specifically, TX followed