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Apolipoprotein E genotype, Alzheimer's pathologies and related gene expression in the aged population

✍ Scribed by Fumitaka Oyama; Hiroyuki Shimada; Rieko Oyama; Yasuo Ihara


Book ID
119138810
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
762 KB
Volume
29
Category
Article
ISSN
0169-328X

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Apolipoprotein E genotypes and age of on
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## Abstract The effect of the apolipoprotein E (APOE) Ο΅4 allele on age of onset was analyzed in two groups of families with early‐onset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) early‐onset non‐VG families showing evidence of linkage