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Apolipoprotein E epsilon 4 is associated with an increased vulnerability to cell death in Alzheimer’s disease

✍ Scribed by C. Frey; A. Bonert; T. Kratzsch; G. Rexroth; W. Rösch; F. Müller-Spahn; K. Maurer; W. E. Müller; A. Eckert


Publisher
Springer
Year
2006
Tongue
English
Weight
206 KB
Volume
113
Category
Article
ISSN
1435-1463

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The apolipoprotein E ε2 allele is associ
✍ Cornelia M. van Duijn; Peter de Knijff; Anita Wehnert; Joke De Voecht; Juliana B 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 652 KB

It was suggested that in contrast to the E4 allele, the E2 allele of the apolipoprotein E gene (APOE"2) has a protective effect for late-onset Alzheimer's disease and early-onset Alzheimer's disease (EOAD). We studied the role of the APOE\*2 allele in the pathogenesis of EOAD in a Dutch population-b