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Apolipoprotein E, amyloid deposition and Alzheimer's disease: Therapeutic implications

Book ID
118577777
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
193 KB
Volume
21
Category
Article
ISSN
0197-4580

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πŸ“œ SIMILAR VOLUMES

APOLIPOPROTEIN E IS ASSOCIATED WITH ISLE
APOLIPOPROTEIN E IS ASSOCIATED WITH ISLET AMYLOID AND OTHER AMYLOIDOSES: IMPLICATIONS FOR ALZHEIMER'S DISEASE
✍ CHARGΓ‰, SOPHIE B. P.; ESIRI, MARGARET M.; BETHUNE, CLAIRE A.; HANSEN, BARBARA C. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 652 KB

Apolipoprotein E (ApoE) has recently been proposed as an aetiological factor of Alzheimer's disease (AD): ApoE is co-localized to amyloid plaques and neurofibrillary tangles in the brain and binds to AP-protein in vitvo. An association of ApoE e4 allele with the development of AD has been reported.