Alzheimer's disease and apolipoprotein e
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M. A. Pericak-Vance; C. C. Johnson; J. B. Rimmler; A. M. Saunders; L. C. Robinso
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Article
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1996
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John Wiley and Sons
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English
β 519 KB
## Abstract Alzheimer's Disease (AD) is a complex genetic disorder with four loci already identified. Mutations in three of these, the amyloid precursor protein, presenilin I, and preseuilin II, cause earlyβonset AD. The apolipoprotein E (APOE) gene contributes primarily to lateβonset AD. The APOEβ