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apoE4, risk factor of Alzheimer's disease, study in young adults

✍ Scribed by Maria Carmen Badia; Ana Lloret; Nancy Mora; Jelena Markovic; Francisco Dasi; Maria Dolores Alonso; Jose Viña


Book ID
118466601
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
60 KB
Volume
6
Category
Article
ISSN
1552-5260

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✍ Houlden, Henry; Crook, Richard; Backhovens, Hubert; Prihar, Guy; Baker, Matt; Hu 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 21 KB 👁 2 views

The apolipoprotein E (ApoE) genotype is a significant risk factor and modulator of age of onset of Alzheimer's disease (AD). We analyzed the effect of the ApoE genotype in two distinct early-onset familial AD groups: families with a mutation in the presenilin-1 gene (PS-1) on chromosome 14, and fami