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APOE ε4 is a high-risk factor for Alzheimer's disease in the Mongolian population

✍ Scribed by Huriletemuer; Binbin Wang; Jing Wang; Guan Wang; Chunyu Zhang; Shigang Zhao; Sirui Zhou; Xu Ma; De Sheng Wang


Book ID
119303548
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
148 KB
Volume
288
Category
Article
ISSN
0022-510X

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The apolipoprotein E (ApoE) genotype is a significant risk factor and modulator of age of onset of Alzheimer's disease (AD). We analyzed the effect of the ApoE genotype in two distinct early-onset familial AD groups: families with a mutation in the presenilin-1 gene (PS-1) on chromosome 14, and fami