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APOE ɛ4, an Alzheimer’s disease susceptibility allele, and smoking cessation

✍ Scribed by Ashare, R L; Karlawish, J H; Wileyto, E P; Pinto, A; Lerman, C

Book ID
120810599
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
369 KB
Volume
13
Category
Article
ISSN
1470-269X

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## Abstract ## Objective The APOE epsilon‐4 allele has consistently emerged as a susceptibility factor for Alzheimer's disease (AD). Pro‐inflammatory cytokines are detectable at abnormal levels in AD, and are thought to play a pathophysiological role. Animal studies have shown dose‐dependent corre