✦ LIBER ✦

Aphidicolin, DNA repair, and fragile sites

✍ Scribed by John A. Reidy

Publisher: Springer
Year: 1988
Tongue: English
Weight: 80 KB
Volume: 78
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00278199

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Fragile sites induced by FUdR, caffeine,

Fragile sites induced by FUdR, caffeine, and aphidicolin

✍ P. Nagesh Rao; Nyla A. Heerema; Catherine G. Palmer 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 492 KB

Population cytogenetics of aphidicolin-i

Population cytogenetics of aphidicolin-induced fragile sites

✍ Bruna Tedeschi; Patrizia Vernole; M.Lucia Sanna; Benedetto Nicoletti 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 433 KB

Chromosome fragile sites are inducible by aphidicolin in cultured human lymphocytes. To assess the frequency and distribution of these common fragile sites in the general population, a cytogenetic survey was performed on 126 subjects, 59 males and 67 females, whose age ranged from 1 day to 72 years.

Fibroblast-specific common fragile sites

Fibroblast-specific common fragile sites induced by aphidicolin

✍ I. Murano; A. Kuwano; T. Kajii 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 469 KB

DNA polymerase α inhibition by aphidicol

DNA polymerase α inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

✍ Thomas W. Glover; Carol Berger; Jane Coyle; Barbara Echo 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 987 KB

Aphidicolin, a specific inhibitor of DNA polymerase alpha, is known to induce chromosomal aberrations. At concentrations that did not greatly affect mitotic index, aphidicolin induced a striking number of chromosome gaps and breaks distributed in a highly nonrandom manner in cultured human lymphocyt

Synergistic effect of aphidicolin and et

Synergistic effect of aphidicolin and ethanol on the induction of common fragile sites

✍ A. Kuwano; T. Kajii 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 615 KB

The effect of ethanol on the frequency of aphidicolin-induced common fragile sites was studied using lymphocyte cultures from two normal women. Aphidicolin was added to the cultures at a final concentration of 0.2 microM and ethanol at 0.02%, 0.1%, 0.2%, 0.5%, and 1%, both during the last 26 h of cu

Aphidicolin-sensitive specific common fr

Aphidicolin-sensitive specific common fragile sites: A biomarker of exposure to pesticides

✍ Antonio Musio; Isabella Sbrana 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 52 KB 👁 2 views

In this work, we analyzed the aphidicolin-sensitive common fragile sites in seven females and four males occupationally exposed to pesticides and in ten controls. The same males had been monitored one year earlier in a previous study by the same authors. Results showed enhanced expression in exposed