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APC promoter hypermethylation is an early event in endometrial tumorigenesis

✍ Scribed by Atanas Ignatov; Joachim Bischoff; Tanja Ignatov; Christa Schwarzenau; Thomas Krebs; Doerthe Kuester; Serban D. Costa; Albert Roessner; Andrzej Semczuk; Regine Schneider-Stock

Book ID
108586572
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
317 KB
Volume
101
Category
Article
ISSN
1347-9032

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Hypermethylation of the somatostatin pro
Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis
✍ Zhe Jin; Yuriko Mori; James P. Hamilton; Alexandru Olaru; Fumiaki Sato; Jian Yan πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 235 KB

## Abstract ## BACKGROUND. The promoter of somatostatin (__SST__), a primary inhibitor of gastrin‐stimulated gastric acid secretion, is hypermethylated in 80% of human colon cancers. The aim of the current study was to investigate whether and at what stage promoter hypermethylation of __SST__ is i