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674 PROMOTER HYPERMETHYLATION OF IGFBP3 IS AN EARLY EVENT IN PROSTATE CARCINOGENESIS

✍ Scribed by A. Perry; B. Loftus; R. Moroose; T. Lynch; D. Hollywood; R.W.G. Watson; K. Woodson; M. Lawler

Book ID
119617993
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
315 KB
Volume
6
Category
Article
ISSN
1569-9056

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## Abstract ## BACKGROUND. The promoter of somatostatin (__SST__), a primary inhibitor of gastrin‐stimulated gastric acid secretion, is hypermethylated in 80% of human colon cancers. The aim of the current study was to investigate whether and at what stage promoter hypermethylation of __SST__ is i