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Antiviral effects of 6-diazo-5-oxo-l-norleucin on replication of herpes simplex virus type 1

โœ Scribed by Jindrich Cinatl; Jens-U Vogel; Jaroslav Cinatl; Hana Kabickova; Bernhard Kornhuber; Hans W Doerr

Book ID
114144858
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
734 KB
Volume
33
Category
Article
ISSN
0166-3542

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Poliovirus and vesicular stomatitis viru
Poliovirus and vesicular stomatitis virus replication in the presence of 6-diazo-5-oxo-L-norleucine or 2-deoxy-D-glucose
โœ Gerald Goldstein; Louis E. Guskey ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 541 KB

The effects of 6-diazo-5-oxo-L-norleucine (DON), 2-deoxy-D-glucose (DOG), and tunicamycin (TM) on the replication of poliovirus (PV) and vesicular stomatitis virus (VSV) were examined. During a 48-hr replication period, TM, DON, and DOG inhibit VSV plaque formation in HEp-2 cells by 99.9%, 99.8%, an