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Antiviral effects and safety of telaprevir, peginterferon alfa-2a, and ribavirin for 28 days in hepatitis C patients

โœ Scribed by Eric Lawitz; Maribel Rodriguez-Torres; Andrew J. Muir; Tara L. Kieffer; Lindsay McNair; Ariya Khunvichai; John G. McHutchison

Book ID
116651601
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
594 KB
Volume
49
Category
Article
ISSN
0168-8278

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Antiviral activity of telaprevir (VX-950
Antiviral activity of telaprevir (VX-950) and peginterferon alfa-2a in patients with hepatitis C
โœ Nicole Forestier; Hendrik W. Reesink; Christine J. Weegink; Lindsay McNair; Tara ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 202 KB

Telaprevir (VX-950), an inhibitor of the hepatitis C virus (HCV) NS3/4A protease, substantially decreased plasma HCV RNA levels in a prior clinical study. The present study evaluated viral kinetics and safety during dosing with telaprevir alone and in combination with peginterferon alfa-2a for 14 da