Clifford A. Brass, 15 and the WIN-R Study Group This prospective, multicenter, community-based and academic-based, open-label, investigator-initiated, U.S. study evaluated efficacy and safety of pegylated interferon (PEG-IFN) alfa-2b plus a flat or weight-based dose of ribavirin (RBV) in adults with
Peginterferon alfa-2a/ribavirin in hepatitis C virus patients nontolerant or nonresponsive to peginterferon alfa-2b/ribavirin
β Scribed by V. K. RUSTGI; S. ESPOSITO; F. M. HAMZEH; M. L. SHIFFMAN
- Book ID
- 108605216
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 87 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0269-2813
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Peginterferon plus ribavirin is standard therapy for adults with chronic hepatitis C. As no data are available for children, the aim of the study was to evaluate the efficacy and tolerability of peginterferon alfa-2b in combination with ribavirin in chronically infected children. Genotypes, alanine
## Abstract Variation at the ILβ28B locus was recently reported to be a significant predictive factor of viral response to pegylatedβinterferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including ILβ28B polymorphism rs8099917 and v
Brass, 14 for the WIN-R Study Group WIN-R (Weight-based dosing of pegINterferon alfa-2b and Ribavirin) was a multicenter, randomized, open-label, investigator-initiated trial involving 236 community and academic sites in the United States, comparing response to pegylated interferon (PEG-IFN) alfa-2b