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Antiviral Effect and Ex Vivo CD4+ T Cell Proliferation in HIV-Positive Patients as a Result of CD28 Costimulation

✍ Scribed by Levine, B. L.; Mosca, J. D.; Riley, J. L.; Carroll, R. G.; Vahey, M. T.; Jagodzinski, L. L.; Wagner, K. F.; Mayers, D. L.; Burke, D. S.; Weislow, O. S.; Louis, D. C. St.; June, C. H.

Book ID
121156403
Publisher
American Association for the Advancement of Science
Year
1996
Tongue
English
Weight
527 KB
Volume
272
Category
Article
ISSN
0036-8075

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## Abstract The role of Treg in patients with late‐stage HIV disease, who commence combination antiretroviral therapy (cART) and develop pathogen‐specific immunopathology manifesting as immune restoration disease (IRD) remains unclear. We hypothesised that Treg could be defective in either numbers