𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Antiviral activity of caspase inhibitors: effect on picornaviral 2A proteinase

✍ Scribed by Luiza Deszcz; Joachim Seipelt; Elena Vassilieva; Andreas Roetzer; Ernst Kuechler

Book ID
117106252
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
190 KB
Volume
560
Category
Article
ISSN
0014-5793

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Structure–Activity relationships within
Structure–Activity relationships within a series of caspase inhibitors: effect of leaving group modifications
✍ Brett R. Ullman; Teresa Aja; Thomas L. Deckwerth; Jose-Luis Diaz; Julia Herrmann πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 178 KB

Various aryloxy methyl ketones of the 1-naphthyloxyacetyl-Val-Asp backbone have been prepared. A systematic study of their structure-activity relationship (SAR) related to caspases 1, 3, 6, and 8 is reported. Highly potent irreversible broad-spectrum caspase inhibitors have been identified. Their ef