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Antiviral action of the tumor suppressor ARF

✍ Scribed by García, María A; Collado, Manuel; Muñoz-Fontela, César; Matheu, Ander; Marcos-Villar, Laura; Arroyo, Javier; Esteban, Mariano; Serrano, Manuel; Rivas, Carmen

Book ID: 110031686
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 224 KB
Volume: 25
Category: Article
ISSN: 0261-4189
DOI: 10.1038/sj.emboj.7601302

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## Abstract The INK4b‐ARF‐INK4a locus encodes two members of the INK4 family of cyclin‐dependent kinase inhibitors, p15^INK4b^ and p16^INK4a^, and a completely unrelated protein called ARF. ARF is a nucleolar protein with unusual structure that exhibits tumor suppressive functions. There is growing