Probenecid in CSF and plasma of rabbits
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W. L. Shei; J. Y. Mu; R. F. Cunningham; Z. H. Israili; P. G. Dayton
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Article
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1977
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Springer
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English
β 336 KB
Probenecid (P) in CSF of rabbits and dogs was investigated using a new radioimmunoassay technique. In rabbits, under steady-state conditions, CSF/free plasma concentration ratios of P were found to be similar to those reported in man. The ratios were concentration dependent and less than 0.5 suggest