Antitumour and immune-adjuvant activities of protein-tyrosine kinase inhibitors
β Scribed by Barbara Seliger; Chiara Massa; Brian Rini; Jennifer Ko; Jim Finke
- Book ID
- 116758249
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 359 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1471-4914
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
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We report a simple method that permits simultaneous detection of multiple protein kinase activities using postnuclear supernatant of \(\mathbf{v}-8\) src transformed NIH3T3 cells. A supernatant is incubated with activators of protein kinases and \(\left[\gamma-{ }^{32} \mathbf{P}\right] \mathrm{ATP}
## Abstract E7080 is an inhibitor of multiple tyrosine kinases, several of which have proβangiogenic properties, including receptors for VEGF, FGF, SCF and PDGF. We undertook our study to evaluate the preclinical activity of E7080 in human sarcomas. The antitumour activity of orally administered E7