Keyphrases 0 Antitumor agents, potential-microhelenin-A, isolated from Helenium microcephalum, NMR spectral identification 0 Microhelenin-A-potential antitumor agent, isolated from Helenium microcephalurn, NMR spectral identification 0 Helenium microcephalum-microhelenin-A, potential antitumor agent
Antitumor sesquiterpene lactones from Helenium microcephalum: Isolation of mexicanin-E and structural characterization of microhelenin-B and -C
โ Scribed by Lee Kuo-Hsiung; Yasuhiro Imakura; Donald Sims; Andrew T. McPhail; Kay D. Onan
- Book ID
- 107841875
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 315 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0031-9422
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๐ SIMILAR VOLUMES
The antitumor sesquiterpene lactones microhelenins-A, B, and C, microlenin acetate, and plenolin were isolated from Helenium microcephalum. The structures and stereochemistry of these lactones were determined by physical methods as well as by chemical transformations and correlations. Microlenin ace
The structure and stereochemistry of mexicanin F, a novel dimeric nor-sesquiterpene lactone isolated from He&n&m mexicanum, have been stablish\_ ed from spectral and single-crystal X-ray analyses. Several years ago, one of us reported the physical constants of the mexicanins A, B,..., H which, in ad
Cytotoxicities for lobatosides B-E and actinostemmosides B-F, isolated from Actinostemma lobatum, were evaluated against a panel of ca 60 human cancer cell lines. Lobatosides B-E (1-4) were cytotoxic (GIs0 < 1 ร 10 -4 M) against all tumor cell lines; 4 showed potent cytotoxicity especially against A