𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Antitumor effects of the fibroblasts transfected TNF-α gene and its mutants

✍ Scribed by Li Qingfen; Li Li; Li Zhuoya; Gong Feili; Feng Wei; Jiang Xiaodan; Xiong Ping

Publisher
Springer-Verlag
Year
2002
Tongue
Chinese
Weight
479 KB
Volume
22
Category
Article
ISSN
0510-9752

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Isolation of the Feline α1,3-Galactosylt
Isolation of the Feline α1,3-Galactosyltransferase Gene, Expression in Transfected Human Cells and its Phylogenetic Analysis
✍ Bibhuti Bhusan Roy; Atsushi Jinno-oue; Masahiko Shinagawa; Akira Shimizu; Kazush 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 583 KB

## Abstract The enzyme alpha 1,3‐galactosyltransferase (α1,3‐GT), which catalyzes synthesis of terminal α‐galactosyl epitopes (Gal α1,3Gal β1‐4GlcNAc‐R), is produced in non‐primate mammals, prosimians and new‐world monkeys, but not in old‐world monkeys, apes and humans. We cloned and sequenced a cD

TNF-α in vivo stimulates apoptosis in fi
TNF-α in vivo stimulates apoptosis in fibroblasts through caspase-8 activation and modulates the expression of pro-apoptotic genes
✍ Mani Alikhani; Zoubin Alikhani; Markos Raptis; Dana T. Graves 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB

## Abstract Apoptosis of matrix producing cells is common among many inflammatory diseases. The goal of the present study was to examine the apoptotic effects of tumor necrosis factor‐α (TNF‐α) on fibroblastic cells in vivo and to investigate the role of different caspases in this process. This was

Effect of polymorphisms of IL-1β and TNF
Effect of polymorphisms of IL-1β and TNF-α genes on CpG island hyper methylation (CIHM) in the nonneoplastic gastric mucosa
✍ Tomomitsu Tahara; Tomoyuki Shibata; Masakatsu Nakamura; Hiromi Yamashita; Daisuk 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 276 KB

## Abstract CpG island hyper methylation (CIHM) is one of the major events in gastric carcinogenesis. To evaluate the influence of host genetic factors in CIHM related carcinogenesis, we investigated the association between common polymorphisms in IL‐1β and TNF‐α genes, with CIHM status in the nonn

Transfected mutant p53 gene increases X-
Transfected mutant p53 gene increases X-ray-induced cell killing and mutation in human fibroblasts immortalized with 4-nitroquinoline 1-oxide but does not induce neoplastic transformation of the cells
✍ Kunihiro Kawashima; Koichiro Mihara; Hisashi Usuki; Nobuyoshi Shimizu; Masayoshi 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 693 KB

We introduced the mutant p53 zene (codon 273Ar9-His) into human fibroblasts (SUSM-I ceils) previously immortalized with 4-nitroquinoline I -oxide (4NQO) and obtained 2 clonal cell lines (SUSM-I /p53-I and SUSM-l/p53-6) expressing the mutant p53. Since the genetic background of SUSM-l/p53 is the same