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Antitumor effect of lipiodolized doxorubicin on VX2 carcinoma in rabbits

✍ Scribed by Toshiya Furuta; Takashi Kanematsu; Takahiro Ezaki; Keizo Sugimachi; Kiyoshi Inokuchi

Book ID
112755470
Publisher
Springer
Year
1985
Tongue
English
Weight
390 KB
Volume
15
Category
Article
ISSN
1436-2813

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When Lipiodol Ultra-Fluid (Lipiodol) was given through arteries feeding the tumor, this material was retained in the tumor. After mixing Lipiodol and doxorubicin (adriamycin; ADR), the effect of this antitumor agent on VX2 carcinoma inoculated into the hindlimb in 57 rabbits was investigated. Size o

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Serum electrolytes, creatinine, urea, protein, albumin, bilirubin and glucose were examined every 4 days until time of death in rabbits with VX-2 carcinoma implanted in one kidney. The rabbits were treated with doxorubicin, nephrectomy or combinations thereof and observed for up to 1 year. Rabbits t