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Antitumor Agents. 183. † Syntheses, Conformational Analyses, and Antitubulin Activity of Allothiocolchicinoids

✍ Scribed by Shi, Qian; Chen, Ke; Chen, Xin; Brossi, Arnold; Verdier-Pinard, Pascal; Hamel, Ernest; McPhail, Andrew T.; Tropsha, Alexander; Lee, Kuo-Hsiung


Book ID
127276355
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
206 KB
Volume
63
Category
Article
ISSN
0022-3263

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To whom correspondence should be addressed ') NMR Assignments: according to the rrivial C-atom numbering as in [6][7] (4.36). 229 (4.25). 'H-NMR: identical with those of 11. CI

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Antitumor Agents. Part 184. Syntheses and Antitubulin Activity of Compounds Derived from Reaction of Thiocolchicone with Amines: Lactams, Alcohols, and Ester Analogues of Allothiocolchicinoids. -Racemic title compounds such as (V) are synthesized and resolved by reaction with (-)-camphanic chloride