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Antitumor Agents. Part 184. Syntheses and antitubulin activity of compounds derived from reaction of thiocolchicone with amines: Lactams, alcohols, and ester analogs of allothiocolchicinoids

✍ Scribed by Qian Shi; Ke Chen; Arnold Brossi; Pascal Verdier-Pinard; Ernest Hamel; Andrew T. McPhail; Kuo-Hsiung Lee

Publisher: John Wiley and Sons
Year: 1998
Tongue: German
Weight: 874 KB
Volume: 81
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.19980810516

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✦ Synopsis

To whom correspondence should be addressed ') NMR Assignments: according to the rrivial C-atom numbering as in [6][7] (4.36). 229 (4.25). 'H-NMR: identical with those of 11. CI

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ChemInform Abstract: Antitumor Agents. P

ChemInform Abstract: Antitumor Agents. Part 184. Syntheses and Antitubulin Activity of Compounds Derived from Reaction of Thiocolchicone with Amines: Lactams, Alcohols, and Ester Analogues of Allothiocolchicinoids.

✍ Q. SHI; K. CHEN; A. BROSSI; P. VERDIER-PINARD; E. HAMEL; A. T. MCPHAIL; K.-H. LE 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Antitumor Agents. Part 184. Syntheses and Antitubulin Activity of Compounds Derived from Reaction of Thiocolchicone with Amines: Lactams, Alcohols, and Ester Analogues of Allothiocolchicinoids. -Racemic title compounds such as (V) are synthesized and resolved by reaction with (-)-camphanic chloride