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Antithrombotic Effects of BCH 2763, a New Direct Thrombin Inhibitor, in a Canine Model of Venous Thrombosis

✍ Scribed by Thomas B. McClanahan; Diane P. Ignasiak; Paul Juneau; Carolyn Finkle; Peter D. Winocour; Kim P. Gallagher


Book ID
110271744
Publisher
Springer US
Year
1999
Tongue
English
Weight
94 KB
Volume
7
Category
Article
ISSN
0929-5305

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Antithrombotic effects of YM466, a synth
✍ Yoshiyuki Iwatsuki; Seiji Kaku; Yumiko Moritani; Yuta Taniuchi; Fukushi Hirayama πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 88 KB

## Abstract The antithrombotic effects of YM466, a synthetic direct inhibitor of human factor Xa (FXa), were evaluated in an arterio‐venous shunt thrombosis model in squirrel monkeys. YM466 significantly inhibited thrombus formation after continuous IV zx infusion at doses of 3–30 Β΅g/kg/h. Although