## Abstract ## Background. Malignant cells show increased glucose uptake in vitro and in vivo, which is thought to be mediated by glucose transporters. In this study, we investigated the effect of plasmidβderived antisense RNA against the Glutβl gene on proliferation and glucose uptake in laryngea
Antisense oligonucleotides for matrilysin inhibit proliferation of human rectal carcinoma cells CaR-1
β Scribed by N Momiyama; T Ishikawa; Y Ichikawa; H Yamaoka; Y Nagashima; K Miyazaki; M Mitsuhashi; H Shimada
- Book ID
- 118880045
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 171 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0016-5085
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Human colon cancer frequently develops liver metastasis. Matrilysin (MMP-7), the smallest member of the matrix metalloproteinase (MMP) family, is commonly produced by human colon carcinoma cells and has been suggested to be involved in the progression and metastasis of this type of cancer. In the pr
## Abstract In recent years, successful examples of antisense oligonucleotide (AS) therapy for genetic diseases have stimulated scientists to investigate its application on cancer diseases. AS can be used to downβregulate the mRNA and protein expression by annealing to specific region of the target