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Antisense oligonucleotide therapy for urologic tumors

✍ Scribed by Ingo Kausch; Andreas Böhle

Book ID
107554770
Publisher
Springer
Year
2003
Tongue
English
Weight
677 KB
Volume
4
Category
Article
ISSN
1527-2737

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Previously we reported hemorrhagic necrosis in human-derived PC-3 prostate tumors, in athymic nude mice, produced by the intralesional injection of antisense oligonucleotides (oligos) directed against mRNAs encoding transforming growth factor-a (TGF-a) and its target, the epidermal growth factor rec