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Antisense oligonucleotide-based therapeutics for cancer

✍ Scribed by Dean, Nicholas M; Bennett, C Frank


Book ID
110068312
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
176 KB
Volume
22
Category
Article
ISSN
0950-9232

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Advances have been made in defining the best target sequences for use in antisense oligonucleotide technology, and new chemical derivatives of oligonucleotides are being investigated. Although the potential use of antisense oligonucleotide agents in the treatment of neoplastic, viral and parasitic d

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✍ Umberto Galderisi; Antonino Cascino; Antonio Giordano πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 126 KB

Antisense oligonucleotides can block the expression of specific target genes involved in the development of human diseases. Therapeutic applications of antisense techniques are currently under investigation in many different fields. The use of antisense molecules to modify gene expression is variabl