𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Antisense oligonucleotides for therapeutic intervention

✍ Scribed by Stephen L. Eck; Gary J. Nabel

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
801 KB
Volume
2
Category
Article
ISSN
0958-1669

No coin nor oath required. For personal study only.

✦ Synopsis

Advances have been made in defining the best target sequences for use in antisense oligonucleotide technology, and new chemical derivatives of oligonucleotides are being investigated. Although the potential use of antisense oligonucleotide agents in the treatment of neoplastic, viral and parasitic diseases continues to be explored, they are not yet suitable for administration to humans for reasons that are discussed.

πŸ“œ SIMILAR VOLUMES

Antisense oligonucleotides as therapeuti
Antisense oligonucleotides as therapeutic agents
✍ Umberto Galderisi; Antonino Cascino; Antonio Giordano πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 126 KB

Antisense oligonucleotides can block the expression of specific target genes involved in the development of human diseases. Therapeutic applications of antisense techniques are currently under investigation in many different fields. The use of antisense molecules to modify gene expression is variabl