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Antisense-mediated VEGF suppression in bladder and breast cancer cells

✍ Scribed by Yvonne Förster; Axel Meye; Sabine Krause; Bernd Schwenzer

Book ID: 116333089
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 291 KB
Volume: 212
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2004.02.020

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## Abstract A specific micro‐RNA (miRNA), micro‐RNA 21 (miR‐21), is strongly overexpressed in breast cancer cells. Antisense inhibition of miRNA function, an important tool for uncovering miRNA biology, which is often used to knockdown miRNA, can cause a notable inhibition of cell growth. In this s