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Amphiregulin antisense RNA delivered by adnovirus suppresses growth of breast cancer cells in vitro and in vivo

✍ Scribed by Ma, Lin ;Randrianarison, Voahangy ;Calvo, Fabien

Book ID: 110671226
Publisher: Springer-Verlag
Year: 2005
Weight: 488 KB
Volume: 2
Category: Article
ISSN: 1672-7118
DOI: 10.1007/bf02761517

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## Abstract A specific micro‐RNA (miRNA), micro‐RNA 21 (miR‐21), is strongly overexpressed in breast cancer cells. Antisense inhibition of miRNA function, an important tool for uncovering miRNA biology, which is often used to knockdown miRNA, can cause a notable inhibition of cell growth. In this s