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Antipsychotic treatment and neuregulin 1–ErbB4 signalling in schizophrenia

✍ Scribed by Bo Pan; Xu-Feng Huang; Chao Deng

Book ID: 116842195
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 438 KB
Volume: 35
Category: Article
ISSN: 0278-5846
DOI: 10.1016/j.pnpbp.2011.04.002

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## Abstract There is now strong evidence that Neuregulin 1 (NRG1) is a susceptibility gene for schizophrenia. NRG1 mediates some of its effects through the tyrosine kinase receptor erbB4, and analysis of gene knock‐out animals suggests that the functional interaction of NRG1 and erbB4 mediates beha