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Antipruritic Dinaphthofuran-7,12-dione Derivatives from the Pericarp of Impatiens balsamina

โœ Scribed by Ishiguro, Kyoko; Ohira, Yukiko; Oku, Hisae

Book ID
121215793
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
75 KB
Volume
61
Category
Article
ISSN
0163-3864

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To investigate the effect of antipruritic agents, we developed an animal model to allow quantitative estimation of itching. Dextran T40 and compound 48/80, agents which cause histamine release, significantly induced scratching behaviour in mice. A 35% ethanol extract (IB) of white petals of Impatien